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Type II Kinase Inhibitors Targeting Cys-Gatekeeper Kinases Display Orthogonality with Wild Type and Ala/Gly-Gatekeeper Kinases., Ocasio CA, Warkentin AA, McIntyre PJ, Barkovich KJ, Vesely C, Spencer J, Shokat KM, Bayliss R., ACS Chem Biol. October 19, 2018; 13 (10): 2956-2965.


The development of the human notochord., de Bree K, de Bakker BS, Oostra RJ., PLoS One. October 4, 2018; 13 (10): e0205752.            


The evolutionary conserved FOXJ1 target gene Fam183b is essential for motile cilia in Xenopus but dispensable for ciliary function in mice., Beckers A, Ott T, Schuster-Gossler K, Boldt K, Alten L, Ueffing M, Blum M, Gossler A., Sci Rep. October 2, 2018; 8 (1): 14678.            


The Xenopus tadpole: An in vivo model to screen drugs favoring remyelination., Mannioui A, Vauzanges Q, Fini JB, Henriet E, Sekizar S, Azoyan L, Thomas JL, Pasquier DD, Giovannangeli C, Demeneix B, Lubetzki C, Zalc B., Mult Scler. October 1, 2018; 24 (11): 1421-1432.


TMEM88 mediates inflammatory cytokines secretion by regulating JNK/P38 and canonical Wnt/β-catenin signaling pathway in LX-2 cells., Xu T, Pan LX, Ge YX, Li P, Meng XM, Huang C, Li J., Inflammopharmacology. October 1, 2018; 26 (5): 1339-1348.


Thyroid hormones and androgens differentially regulate gene expression in testes and ovaries of sexually mature Silurana tropicalis., Campbell DEK, Langlois VS., Gen Comp Endocrinol. October 1, 2018; 267 172-182.            


The b-HLH transcription factor Hes3 participates in neural plate border formation by interfering with Wnt/β-catenin signaling., Hong CS, Saint-Jeannet JP., Dev Biol. October 1, 2018; 442 (1): 162-172.                


Tight junction-associated protein GEF-H1 in the neighbours of dividing epithelial cells is essential for adaptation of cell-cell membrane during cytokinesis., Hatte G, Prigent C, Tassan JP., Exp Cell Res. October 1, 2018; 371 (1): 72-82.


Two mutations at different positions in the CNBH domain of the hERG channel accelerate deactivation and impair the interaction with the EAG domain., Kume S, Shimomura T, Tateyama M, Kubo Y., J Physiol. October 1, 2018; 596 (19): 4629-4650.


The small molecule AMBMP disrupts microtubule growth, ciliogenesis, cell polarity, and cell migration., Werner M, Del Castillo U, Ventrella R, Brotslaw E, Mitchell B., Cytoskeleton (Hoboken). October 1, 2018; 75 (10): 450-457.


The Conorfamide RPRFa Stabilizes the Open Conformation of Acid-Sensing Ion Channel 3 via the Nonproton Ligand-Sensing Domain., Reiners M, Margreiter MA, Oslender-Bujotzek A, Rossetti G, Gründer S, Schmidt A., Mol Pharmacol. October 1, 2018; 94 (4): 1114-1124.


The nucleoside-diphosphate kinase NME3 associates with nephronophthisis proteins and is required for ciliary function during renal development., Hoff S, Epting D, Falk N, Schroda S, Braun DA, Halbritter J, Hildebrandt F, Kramer-Zucker A, Bergmann C, Walz G, Lienkamp SS., J Biol Chem. September 28, 2018; 293 (39): 15243-15255.            


The Xenopus animal cap transcriptome: building a mucociliary epithelium., Angerilli A, Smialowski P, Rupp RA., Nucleic Acids Res. September 28, 2018; 46 (17): 8772-8787.                          


The cytoskeletal protein Zyxin interacts with the zinc-finger transcription factor Zic1 and plays the role of a scaffold for Gli1 and Zic1 interactions during early development of Xenopus laevis., Martynova NY, Parshina EA, Ermolina LV, Zaraisky AG., Biochem Biophys Res Commun. September 26, 2018; 504 (1): 251-256.


The roles of aromatic residues in the glycine receptor transmembrane domain., Tang B, Lummis SCR., BMC Neurosci. September 6, 2018; 19 (1): 53.                  


The TMEM16A channel mediates the fast polyspermy block in Xenopus laevis., Wozniak KL, Phelps WA, Tembo M, Lee MT, Carlson AE., J Gen Physiol. September 3, 2018; 150 (9): 1249-1259.          


The fast block to polyspermy: New insight into a century-old problem., Jaffe LA., J Gen Physiol. September 3, 2018; 150 (9): 1233-1234.


Tectal CRFR1 receptors modulate food intake and feeding behavior in the South African clawed frog Xenopus laevis., Prater CM, Harris BN, Carr JA., Horm Behav. September 1, 2018; 105 86-94.


TBC1d24-ephrinB2 interaction regulates contact inhibition of locomotion in neural crest cell migration., Yoon J, Hwang YS, Lee M, Sun J, Cho HJ, Knapik L, Daar IO., Nat Commun. August 28, 2018; 9 (1): 3491.  


Temporal Regulation of ESCO2 Degradation by the MCM Complex, the CUL4-DDB1-VPRBP Complex, and the Anaphase-Promoting Complex., Minamino M, Tei S, Negishi L, Kanemaki MT, Yoshimura A, Sutani T, Bando M, Shirahige K., Curr Biol. August 20, 2018; 28 (16): 2665-2672.e5.


The role of pparγ in embryonic development of Xenopus tropicalis under triphenyltin-induced teratogenicity., Zhu J, Huang X, Jiang H, Hu L, Michal JJ, Jiang Z, Shi H., Sci Total Environ. August 15, 2018; 633 1245-1252.


Time-lapse imaging of cell death in cell culture and whole living organisms using turn-on deep-red fluorescent probes., Jarvis TS, Roland FM, Dubiak KM, Huber PW, Smith BD., J Mater Chem B. August 14, 2018; 6 (30): 4963-4971.


The RNA-binding complex ESCRT-II in Xenopus laevis eggs recognizes purine-rich sequences through its subunit, Vps25., Emerman AB, Blower MD., J Biol Chem. August 10, 2018; 293 (32): 12593-12605.          


The age-regulated zinc finger factor ZNF367 is a new modulator of neuroblast proliferation during embryonic neurogenesis., Naef V, Monticelli S, Corsinovi D, Mazzetto MT, Cellerino A, Ori M., Sci Rep. August 7, 2018; 8 (1): 11836.                      


Toward an Ensemble View of Chromatosome Structure: A Paradigm Shift from One to Many., Öztürk MA, Cojocaru V, Wade RC., Structure. August 7, 2018; 26 (8): 1050-1057.


The N terminus of α-ENaC mediates ENaC cleavage and activation by furin., Kota P, Gentzsch M, Dang YL, Boucher RC, Stutts MJ., J Gen Physiol. August 6, 2018; 150 (8): 1179-1187.              


Thiodipeptides targeting the intestinal oligopeptide transporter as a general approach to improving oral drug delivery., Foley DW, Pathak RB, Phillips TR, Wilson GL, Bailey PD, Pieri M, Senan A, Meredith D., Eur J Med Chem. August 5, 2018; 156 180-189.            


The permeation mechanism of organic cations through a CNG mimic channel., Napolitano LMR, Marchesi A, Rodriguez A, De March M, Onesti S, Laio A, Torre V., PLoS Comput Biol. August 2, 2018; 14 (8): e1006295.          


The fungal alkaloid Okaramine-B activates an L-glutamate-gated chloride channel from Ixodes scapularis, a tick vector of Lyme disease., Furutani S, Ihara M, Lees K, Buckingham SD, Partridge FA, David JA, Patel R, Warchal S, Mellor IR, Matsuda K, Sattelle DB., Int J Parasitol Drugs Drug Resist. August 1, 2018; 8 (2): 350-360.                


The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders., Willsey AJ, Morris MT, Wang S, Willsey HR, Sun N, Teerikorpi N, Baum TB, Cagney G, Bender KJ, Desai TA, Srivastava D, Davis GW, Doudna J, Chang E, Sohal V, Lowenstein DH, Li H, Agard D, Keiser MJ, Shoichet B, von Zastrow M, Mucke L, Finkbeiner S, Gan L, Sestan N, Ward ME, Huttenhain R, Nowakowski TJ, Bellen HJ, Frank LM, Khokha MK, Lifton RP, Kampmann M, Ideker T, State MW, Krogan NJ., Cell. July 26, 2018; 174 (3): 505-520.      


Triheteromeric GluN1/GluN2A/GluN2C NMDARs with Unique Single-Channel Properties Are the Dominant Receptor Population in Cerebellar Granule Cells., Bhattacharya S, Khatri A, Swanger SA, DiRaddo JO, Yi F, Hansen KB, Yuan H, Traynelis SF., Neuron. July 25, 2018; 99 (2): 315-328.e5.                      


The left-right asymmetry of liver lobation is generated by Pitx2c-mediated asymmetries in the hepatic diverticulum., Womble M, Amin NM, Nascone-Yoder N., Dev Biol. July 15, 2018; 439 (2): 80-91.                  


Transcriptomics of dorso-ventral axis determination in Xenopus tropicalis., Monteiro RS, Gentsch GE, Smith JC., Dev Biol. July 15, 2018; 439 (2): 69-79.                                    


The degenerin region of the human bile acid-sensitive ion channel (BASIC) is involved in channel inhibition by calcium and activation by bile acids., Ilyaskin AV, Kirsch SA, Böckmann RA, Sticht H, Korbmacher C, Haerteis S, Diakov A., Pflugers Arch. July 1, 2018; 470 (7): 1087-1102.


Tbx2 is required for the suppression of mesendoderm during early Xenopus development., Teegala S, Chauhan R, Lei E, Weinstein DC., Dev Dyn. July 1, 2018; 247 (7): 903-913.                


The Calcium-Sensing Receptor Increases Activity of the Renal NCC through the WNK4-SPAK Pathway., Bazúa-Valenti S, Rojas-Vega L, Castañeda-Bueno M, Barrera-Chimal J, Bautista R, Cervantes-Pérez LG, Vázquez N, Plata C, Murillo-de-Ozores AR, González-Mariscal L, Ellison DH, Riccardi D, Bobadilla NA, Gamba G., J Am Soc Nephrol. July 1, 2018; 29 (7): 1838-1848.


The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT3 receptor expressing interneurons: An in vitro study in rat hippocampus slices., Dale E, Grunnet M, Pehrson AL, Frederiksen K, Larsen PH, Nielsen J, Stensbøl TB, Ebert B, Yin H, Lu D, Liu H, Jensen TN, Yang CR, Sanchez C., Brain Res. June 15, 2018; 1689 1-11.


The proteoglycan-like domain of carbonic anhydrase IX mediates non-catalytic facilitation of lactate transport in cancer cells., Ames S, Pastorekova S, Becker HM., Oncotarget. June 15, 2018; 9 (46): 27940-27957.                    


TRRAP is a central regulator of human multiciliated cell formation., Wang Z, Plasschaert LW, Aryal S, Renaud NA, Yang Z, Choo-Wing R, Pessotti AD, Kirkpatrick ND, Cochran NR, Carbone W, Maher R, Lindeman A, Russ C, Reece-Hoyes J, McAllister G, Hoffman GR, Roma G, Jaffe AB., J Cell Biol. June 4, 2018; 217 (6): 1941-1955.                        


TGF-β Family Signaling in Early Vertebrate Development., Zinski J, Tajer B, Mullins MC., Cold Spring Harb Perspect Biol. June 1, 2018; 10 (6):


The atypical mitogen-activated protein kinase ERK3 is essential for establishment of epithelial architecture., Takahashi C, Miyatake K, Kusakabe M, Nishida E., J Biol Chem. June 1, 2018; 293 (22): 8342-8361.                                      


The dynamics of gene expression in vertebrate embryogenesis at single-cell resolution., Briggs JA, Weinreb C, Wagner DE, Megason S, Peshkin L, Kirschner MW, Klein AM., Science. June 1, 2018; 360 (6392):       


The eukaryotic bell-shaped temporal rate of DNA replication origin firing emanates from a balance between origin activation and passivation., Arbona JM, Goldar A, Hyrien O, Arneodo A, Audit B., Elife. June 1, 2018; 7     


The fifth subunit of the (α4β2)2 β2 nicotinic ACh receptor modulates maximal ACh responses., New K, Del Villar SG, Mazzaferro S, Alcaino C, Bermudez I., Br J Pharmacol. June 1, 2018; 175 (11): 1822-1837.


The VLDL receptor regulates membrane progesterone receptor trafficking and non-genomic signaling., Nader N, Dib M, Courjaret R, Hodeify R, Machaca R, Graumann J, Machaca K., J Cell Sci. May 23, 2018; 131 (10):                 


The Ajuba family protein Wtip regulates actomyosin contractility during vertebrate neural tube closure., Chu CW, Xiang B, Ossipova O, Ioannou A, Sokol SY., J Cell Sci. May 16, 2018; 131 (10):


Transcriptome of Xenopus andrei, an octoploid frog, during embryonic development., Pownall ME, Cutler RR, Saha MS., Data Brief. May 16, 2018; 19 501-505.  


TRESK background potassium channel is not gated at the helix bundle crossing near the cytoplasmic end of the pore., Lengyel M, Czirják G, Enyedi P., PLoS One. May 15, 2018; 13 (5): e0197622.          


The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels., García IE, Villanelo F, Contreras GF, Pupo A, Pinto BI, Contreras JE, Pérez-Acle T, Alvarez O, Latorre R, Martínez AD, González C., J Gen Physiol. May 7, 2018; 150 (5): 697-711.                          


Tooth germ initiation patterns in a developing dentition: An in vivo study of Xenopus laevis tadpoles., Lamoureux DO, LeBlanc ARH, Caldwell MW., J Morphol. May 1, 2018; 279 (5): 616-625.

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